EXOSC1 antibody

Catalog No. ABIN5963401

Product Details anti-EXOSC1 Antibody

Target: EXOSC1 (Exosome Component 1 (EXOSC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human EXOSC1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXOSC1

Target: EXOSC1 (Exosome Component 1 (EXOSC1))

Alternative Name: EXOSC1 (EXOSC1 Products)

Synonyms: MGC86284 antibody, CGI-108 antibody, CSL4 antibody, Csl4p antibody, SKI4 antibody, Ski4p antibody, hCsl4p antibody, p13 antibody, 2610035C18Rik antibody, 2610104C07Rik antibody, 2610312F07Rik antibody, AI447561 antibody, exosome component 1 antibody, exosome component 1 L homeolog antibody, EXOSC1 antibody, exosc1.L antibody, exosc1 antibody, PTRG_05845 antibody, Exosc1 antibody

Background:

Synonyms: 3'-5' exoribonuclease CSL4 homolog,CGI 108,CGI-108,CSL4,CSL4 exosomal core protein homolog,CSL4, S. cerevisiae, homolog of,Csl4p,EXOS1,Exosc1,Exosomal core protein CSL4,Exosome complex component csl4,Exosome component 1,hCsl4p,Homolog of yeast exosomal core protein CSL4,p13,RP11-452K12.9,SKI4,Ski4p

Background: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight:

Observed_MW: 21kDa

Calculated_MW: 21kDa

Gene ID: 51013

UniProt: Q9Y3B2