Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

EBP antibody

EBP Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5963984
  • Target See all EBP Antibodies
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Reactivity
    • 41
    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 42
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 16
    • 6
    • 6
    • 6
    • 4
    • 4
    This EBP antibody is un-conjugated
    Application
    • 34
    • 33
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human EBP
    Isotype
    IgG
    Top Product
    Discover our top product EBP Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Alternative Name
    EBP (EBP Products)
    Synonyms
    cdpx2 antibody, cho2 antibody, cpx antibody, cpxd antibody, zgc:91895 antibody, CDPX2 antibody, CHO2 antibody, CPX antibody, CPXD antibody, AI255399 antibody, Pabp antibody, Td antibody, mSI antibody, emopamil binding protein (sterol isomerase) antibody, emopamil binding protein (sterol isomerase) L homeolog antibody, phenylalkylamine Ca2+ antagonist (emopamil) binding protein antibody, Ebp antibody, ebp.L antibody, ebp antibody, EBP antibody
    Background

    Synonyms: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,CDPX2 ,CHO2,Cholestenol Delta-isomerase,CPX,CPXD,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,ebp,EBP,Emopamil-binding protein,Msi

    Background: The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).

    Molecular Weight

    Observed_MW: 26kDa

    Calculated_MW: 26kDa

    Gene ID
    10682
    UniProt
    Q15125
You are here:
Support