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TPSAB1 antibody

TPSAB1 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5964282
  • Target See all TPSAB1 Antibodies
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    Reactivity
    • 47
    • 34
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 67
    • 19
    • 2
    • 1
    Rabbit
    Clonality
    • 72
    • 17
    Polyclonal
    Conjugate
    • 46
    • 17
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPSAB1 antibody is un-conjugated
    Application
    • 71
    • 40
    • 27
    • 12
    • 11
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TPSAB1 (NP_003285.2).
    Isotype
    IgG
    Top Product
    Discover our top product TPSAB1 Primary Antibody
  • Application Notes
    IF 1:20-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    Alternative Name
    TPSAB1 (TPSAB1 Products)
    Synonyms
    TPS1 antibody, TPS2 antibody, TPSB1 antibody, PMCT7 antibody, tpsab1 antibody, tryptaseB antibody, tryptaseC antibody, MMCP-7 antibody, Mcp-7 antibody, Mcp7 antibody, Mcpt7 antibody, rMCP-7 antibody, AV011504 antibody, MMCP-6 antibody, Mcp-6 antibody, Mcp6 antibody, Mcpt6 antibody, tryptase alpha/beta 1 antibody, tryptase antibody, tryptase beta 2 (gene/pseudogene) antibody, tryptase beta 2 antibody, TPSAB1 antibody, MCT7 antibody, tpsab1 antibody, TPSB2 antibody, Tpsab1 antibody, Tpsb2 antibody
    Background
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
    Molecular Weight

    Observed_MW: 33kDa

    Calculated_MW: 29kDa/30kDa

    Gene ID
    7177
    UniProt
    Q15661
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