ARAP1 antibody

Catalog No. ABIN5964546

Product Details anti-ARAP1 Antibody

Target: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ARAP1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARAP1

Target: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Alternative Name: ARAP1 (ARAP1 Products)

Synonyms: CENTD2 antibody, ARAP1 antibody, Ci-ArfGAP-8 antibody, 2410002L19Rik antibody, Centd2 antibody, mKIAA0782 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 antibody, centaurin, delta 2 antibody, ARAP1 antibody, centd2 antibody, Arap1 antibody

Background:

Synonyms: 2410002L19Rik,ANK repeat and PH domain-containing protein 1,ARAP 1,Arap1,ARAP1,Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1,Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1,Arf-GAP with Rho-GAP domain,CENT D2,Centaurin delta 2,Centaurin delta2,Centaurin-delta-2,CENTD 2,CENTD2,Cnt d2,Cnt-d2,Cntd2,KIAA0782,MGC176140,mKIAA0782

Background: The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 190kDa

Calculated_MW: 77kDa/127kDa/135kDa/136kDa/160kDa/162kDa

Gene ID: 116985

UniProt: Q96P48