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alpha KGDHC antibody

alphaKGDHC Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5966581
  • Target See all alpha KGDHC (alphaKGDHC) Antibodies
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Reactivity
    • 38
    • 12
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 37
    • 1
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This alpha KGDHC antibody is un-conjugated
    Application
    • 27
    • 20
    • 19
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human OGDH (NP_001003941.1).
    Isotype
    IgG
    Top Product
    Discover our top product alphaKGDHC Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    Alternative Name
    OGDH (alphaKGDHC Products)
    Synonyms
    AKGDH antibody, E1k antibody, OGDC antibody, 2210403E04Rik antibody, 2210412K19Rik antibody, AA409584 antibody, d1401 antibody, mKIAA4192 antibody, oxoglutarate dehydrogenase antibody, oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) antibody, OGDH antibody, Ogdh antibody
    Background
    This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight

    Observed_MW: 116kDa

    Calculated_MW: 48kDa/115kDa

    Gene ID
    4967
    UniProt
    Q02218
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