GPSM2 antibody

Catalog No. ABIN5966852

Product Details anti-GPSM2 Antibody

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPSM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GPSM2 (NP_037428.3).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GPSM2

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Alternative Name: GPSM2 (GPSM2 Products)

Synonyms: CMCS antibody, DFNB82 antibody, LGN antibody, PINS antibody, dfnb82 antibody, lgn antibody, pins antibody, RGD1560967 antibody, Pinsa antibody, zgc:63574 antibody, 6230410J09Rik antibody, Pins antibody, G protein signaling modulator 2 antibody, G-protein signaling modulator 2 S homeolog antibody, G-protein signaling modulator 2 antibody, G-protein signalling modulator 2 (AGS3-like, C. elegans) antibody, GPSM2 antibody, gpsm2.S antibody, Gpsm2 antibody, gpsm2 antibody

Background: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 77kDa

Calculated_MW: 76kDa

Gene ID: 29899

UniProt: P81274

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling