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Aggrecan antibody (AA 20-280)

ACAN Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6127417
  • Target See all Aggrecan (ACAN) Antibodies
    Aggrecan (ACAN)
    Binding Specificity
    • 15
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-280
    Reactivity
    • 67
    • 55
    • 40
    • 31
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 80
    • 18
    • 1
    Rabbit
    Clonality
    • 73
    • 26
    Polyclonal
    Conjugate
    • 47
    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Aggrecan antibody is un-conjugated
    Application
    • 71
    • 40
    • 26
    • 26
    • 26
    • 20
    • 16
    • 12
    • 8
    • 8
    • 4
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    VETSDHDNSL SVSIPQPSPL RVLLGTSLTI PCYFIDPMHP VTTAPSTAPL APRIKWSRVS KEKEVVLLVA TEGRVRVNSA YQDKVSLPNY PAIPSDATLE VQSLRSNDSG VYRCEVMHGI EDSEATLEVV VKGIVFHYRA ISTRYTLDFD RAQRACLQNS AIIATPEQLQ AAYEDGFHQC DAGWLADQTV RYPIHTPREG CYGDKDEFPG VRTYGIRDTN ETYDVYCFAE EMEGEVFYAT SPEKFTFQEA ANECRRLGAR L
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human Aggrecan (NP_001126.3).
    Isotype
    IgG
    Top Product
    Discover our top product ACAN Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Aggrecan (ACAN)
    Alternative Name
    ACAN (ACAN Products)
    Synonyms
    AGC1 antibody, AGCAN antibody, CSPG1 antibody, CSPGCP antibody, MSK16 antibody, SEDK antibody, Agc antibody, Agc1 antibody, Cspg1 antibody, b2b183Clo antibody, cmd antibody, aggrecan antibody, aggrecan core protein antibody, ACAN antibody, Acan antibody, LOC100380783 antibody, AGC antibody
    Background
    This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.,ACAN,AGC1,AGCAN,CSPG1,CSPGCP,MSK16,SEDK,aggrecan,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Stem Cells,Mesenchymal Stem Cells,ACAN
    Molecular Weight
    239 kDa/246 kDa/250 kDa
    Gene ID
    176
    UniProt
    P16112
    Pathways
    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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