Transferrin Receptor 2 antibody (AA 582-801)

Catalog No. ABIN6149063

Product Details anti-Transferrin Receptor 2 Antibody

Target: Transferrin Receptor 2 (TFR2)

Binding Specificity: AA 582-801

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transferrin Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: AVEFSFMEDD QAYPFLHTKE DTYENLHKVL QGRLPAVAQA VAQLAGQLLI RLSHDRLLPL DFGRYGDVVL RHIGNLNEFS GDLKARGLTL QWVYSARGDY IRAAEKLRQE IYSSEERDER LTRMYNVRIM RVEFYFLSQY VSPADSPFRH IFMGRGDHTL GALLDHLRLL RSNSSGTPGA TSSTGFQESR FRRQLALLTW TLQGAANALS GDVWNIDNNF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 582-801 of human TFR2 (NP_003218.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Transferrin Receptor 2

Target: Transferrin Receptor 2 (TFR2)

Alternative Name: TFR2 (TFR2 Products)

Synonyms: TFR2 antibody, Trfr2 antibody, HFE3 antibody, TFRC2 antibody, zgc:123043 antibody, transferrin receptor 2 antibody, TFR2 antibody, Tfr2 antibody, tfr2 antibody

Background: This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TFR2,HFE3,TFRC2,Cancer,Signal Transduction,Endocrine & Metabolism,Cardiovascular,Blood,TFR2

Molecular Weight: 69 kDa/86 kDa/88 kDa

Gene ID: 7036

UniProt: Q9UP52

Pathways: Transition Metal Ion Homeostasis