CYP3A5 antibody (AA 233-502)

Catalog No. ABIN6139354

Product Details anti-CYP3A5 Antibody

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Binding Specificity: AA 233-502

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP3A5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FEALNVSLFP KDTINFLSKS VNRMKKSRLN DKQKHRLDFL QLMIDSQNSK ETESHKALSD LELAAQSIIF IFAGYETTSS VLSFTLYELA THPDVQQKLQ KEIDAVLPNK APPTYDAVVQ MEYLDMVVNE TLRLFPVAIR LERTCKKDVE INGVFIPKGS MVVIPTYALH HDPKYWTEPE EFRPERFSKK KDSIDPYIYT PFGTGPRNCI GMRFALMNMK LALIRVLQNF SFKPCKETQI PLKLDTQGLL QPEKPIVLKV DSRDGTLSGE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 233-502 of human CYP3A5 (NP_000768.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP3A5

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Alternative Name: CYP3A5 (CYP3A5 Products)

Synonyms: CP35 antibody, CYPIIIA5 antibody, P450PCN3 antibody, PCN3 antibody, cytochrome P450 family 3 subfamily A member 5 antibody, CYP3A5 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.,CYP3A5,CP35,CYPIIIA5,P450PCN3,PCN3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP3A5

Molecular Weight: 15 kDa/57 kDa

Gene ID: 1577

UniProt: P20815

Pathways: Steroid Hormone Biosynthesis