PIP5K1B antibody (AA 190-470)

Catalog No. ABIN6145684

Product Details anti-PIP5K1B Antibody

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Binding Specificity: AA 190-470

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIP5K1B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: NVLPRSMRMH FTYDLKGSTY KRRASRKERE KSNPTFKDLD FLQDMHEGLY FDTETYNALM KTLQRDCRVL ESFKIMDYSL LLGIHFLDHS LKEKEEETPQ NVPDAKRTGM QKVLYSTAME SIQGPGKSGD GIITENPDTM GGIPAKSHRG EKLLLFMGII DILQSYRLMK KLEHSWKALV YDGDTVSVHR PSFYADRFLK FMNSRVFKKI QALKASPSKK RCNSIAALKA TSQEIVSSIS QEWKDEKRDL LTEGQSFSSL DEEALGSRHR PDLVPSTPSL F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-470 of human PIP5K1B (NP_003549.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIP5K1B

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Alternative Name: PIP5K1B (PIP5K1B Products)

Synonyms: MSS4 antibody, STM7 antibody, AI844522 antibody, Pip5k1a antibody, Pipk5a antibody, Pipk5b antibody, MGC80809 antibody, pip5k1b antibody, zgc:101046 antibody, wu:fj29b05 antibody, wu:fj93b05 antibody, zgc:92316 antibody, phosphatidylinositol-4-phosphate 5-kinase type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta a antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta antibody, phosphatidylinositol 4-phosphate 5-kinase type-1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta b antibody, PIP5K1B antibody, Pip5k1b antibody, pip5k1b.L antibody, pip5k1ba antibody, pip5k1b antibody, LOC100472550 antibody, pip5k1bb antibody

Background: Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4P/PI4P to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5P2/PIP2, a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity. PtdIns(4,5P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3, diacylglycerol (DAG or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5P3/PIP3 (By similarity. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G-protein coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion (By similarity.,PIP5K1B,MSS4,STM7,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Actins,PIP5K1B

Molecular Weight: 56 kDa/61 kDa/62 kDa

Gene ID: 8395

UniProt: O14986

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization