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ACOX1 antibody (AA 1-270)

ACOX1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6131168
  • Target See all ACOX1 Antibodies
    ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
    Binding Specificity
    • 9
    • 9
    • 8
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1-270
    Reactivity
    • 72
    • 22
    • 3
    Human
    Host
    • 67
    • 6
    Rabbit
    Clonality
    • 57
    • 16
    Polyclonal
    Conjugate
    • 33
    • 8
    • 8
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACOX1 antibody is un-conjugated
    Application
    • 56
    • 49
    • 19
    • 16
    • 8
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MNPDLRRERD SASFNPELLT HILDGSPEKT RRRREIENMI LNDPDFQHED LNFLTRSQRY EVAVRKSAIM VKKMREFGIA DPDEIMWFKN FVHRGRPEPL DLHLGMFLPT LLHQATAEQQ ERFFMPAWNL EIIGTYAQTE MGHGTHLRGL ETTATYDPET QEFILNSPTV TSIKWWPGGL GKTSNHAIVL AQLITKGKCY GLHAFIVPIR EIGTHKPLPG ITVGDIGPKF GYDEIDNGYL KMDNHRIPRE NMLMKYAQVK PDGTYVKPLS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACOX1 (NP_004026.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yan, Li, Peng, Long, Fan, Wang, Shi, Xie, Zhao, Yan: "The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study." in: Scientific reports, Vol. 7, Issue 1, pp. 1914, (2018) (PubMed).

    Long, Muhamad, Yan, Yu, Fan, Wang, Li, Purnomoadi, Achmadi, Yan: "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells." in: Amino acids, Vol. 48, Issue 5, pp. 1297-307, (2017) (PubMed).

  • Target
    ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
    Alternative Name
    ACOX1 (ACOX1 Products)
    Synonyms
    zgc:92584 antibody, wu:fb59h12 antibody, zgc:114033 antibody, aco antibody, acox antibody, ACOX antibody, PALMCOX antibody, SCOX antibody, RATACOA1 antibody, AOX antibody, Acox antibody, D130055E20Rik antibody, Paox antibody, PCOX1 antibody, acyl-CoA oxidase 1 antibody, acyl-CoA oxidase 1, palmitoyl antibody, acyl-CoA oxidase 1, palmitoyl L homeolog antibody, acyl-Coenzyme A oxidase 1, palmitoyl antibody, ACOX1 antibody, acox1 antibody, acox1.L antibody, Acox1 antibody
    Background
    The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.,ACOX1,ACOX,PALMCOX,SCOX,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ACOX1
    Molecular Weight
    70 kDa/74 kDa
    Gene ID
    51
    UniProt
    Q15067
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
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