ALOX5 antibody (pSer271)
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- Target See all ALOX5 Antibodies
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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Binding Specificity
- pSer271
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ALOX5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QLSLE
- Cross-Reactivity
- Human
- Characteristics
- Phosphorylated Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around S271 of human ALOX5 (NP_000689.1).
- Isotype
- IgG
- Top Product
- Discover our top product ALOX5 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
- Alternative Name
- ALOX5 (ALOX5 Products)
- Synonyms
- 5-LO antibody, 5-LOX antibody, 5LPG antibody, LOG5 antibody, 5LO antibody, 5LX antibody, AI850497 antibody, F730011J02 antibody, LOX5A antibody, si:dkey-194n13.2 antibody, lox5 antibody, arachidonate 5-lipoxygenase antibody, arachidonate 5-lipoxygenase a antibody, Arachidonate 5-lipoxygenase antibody, ALOX5 antibody, Alox5 antibody, alox5a antibody, AFUA_4G02770 antibody, AOR_1_1362014 antibody, lox5 antibody
- Background
- This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ALOX5,5-LO,5-LOX,5LPG,LOG5,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Protein phosphorylation,ALOX5
- Molecular Weight
- 56 kDa/61 kDa/71 kDa/74 kDa/77 kDa
- Gene ID
- 240
- UniProt
- P09917
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