ABCD1 antibody (AA 340-500)

Catalog No. ABIN6136369

This Rabbit Polyclonal antibody specifically detects ABCD1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for ABCD1 antibody (AA 340-500) (ABIN6136369)

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ABCD1 Antibody

Binding Specificity: AA 340-500

Sequence: SASGLLMVAV PIITATGYSE SDAEAVKKAA LEKKEEELVS ERTEAFTIAR NLLTAAADAI ERIMSSYKEV TELAGYTARV HEMFQVFEDV QRCHFKRPRE LEDAQAGSGT IGRSGVRVEG PLKIRGQVVD VEQGIICENI PIVTPSGEVV VASLNIRVEE G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 340-500 of human ABCD1 (NP_000024.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABCD1

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Alternative Name: ABCD1

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.,ABCD1,ABC42,ALD,ALDP,AMN,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ABCD1

Molecular Weight: 82 kDa

Gene ID: 215

UniProt: P33897

Pathways: Monocarboxylic Acid Catabolic Process