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ALOXE3 antibody (AA 1-280)

ALOXE3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6136821
  • Target See all ALOXE3 Antibodies
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-280
    Reactivity
    • 40
    • 8
    Human
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALOXE3 antibody is un-conjugated
    Application
    • 24
    • 18
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MAVYRLCVTT GPYLRAGTLD NISVTLVGTC GESPKQRLDR MGRDFAPGSV QKYKVRCTAE LGELLLLRVH KERYAFFRKD SWYCSRICVT EPDGSVSHFP CYQWIEGYCT VELRPGTART ICQDSLPLLL DHRTRELRAR QECYRWKIYA PGFPCMVDVN SFQEMESDKK FALTKTTTCV DQGDSSGNRY LPGFPMKIDI PSLMYMEPNV RYSATKTISL LFNAIPASLG MKLRGLLDRK GSWKKLDDMQ NIFWCHKTFT TKYVTEHWCE DHFFGYQYLN
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALOXE3 (NP_067641.2).
    Isotype
    IgG
    Top Product
    Discover our top product ALOXE3 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))
    Alternative Name
    ALOXE3 (ALOXE3 Products)
    Synonyms
    e-lox antibody, elox3 antibody, ARCI3 antibody, E-LOX antibody, eLOX3 antibody, e-LOX-3 antibody, ALOX15B antibody, arachidonate lipoxygenase 3 antibody, arachidonate lipoxygenase 3 L homeolog antibody, arachidonate 15-lipoxygenase, type B antibody, ALOXE3 antibody, aloxe3.L antibody, aloxe3 antibody, Aloxe3 antibody, ALOX15B antibody
    Background
    This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.,ALOXE3,ARCI3,E-LOX,eLOX-3,eLOX3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,ALOXE3
    Molecular Weight
    80 kDa/95 kDa
    Gene ID
    59344
    UniProt
    Q9BYJ1
    Pathways
    Cell-Cell Junction Organization
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