ARAP2 antibody (AA 1405-1704)

Catalog No. ABIN6137061

Product Details anti-ARAP2 Antibody

Target: ARAP2 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))

Binding Specificity: AA 1405-1704

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LAEPGSAYLV VKRFLTADTI KHCSDRSTLG SIKEGILKIK EEPSKILSGN KFQDRYFVLR DGFLFLYKDV KSSKHDKMFS LSSMKFYRGV KKKMKPPTSW GLTAYSEKHH WHLCCDSSRT QTEWMTSIFI AQHEYDIWPP AGKERKRSIT KNPKIGGLPL IPIQHEGNAT LARKNIESAR AELERLRLSE KCDKESVDSS LKERASMVAH CLEHKDDKLR NRPRKHRSFN CLEDTEPEAP LGQPKGHKGL KTLRKTEDRN SKATLDSDHK LPSRVIEELN VVLQRSRTLP KELQDEQILK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1405-1704 of human ARAP2 (NP_056045.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARAP2

Target: ARAP2 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))

Alternative Name: ARAP2 (ARAP2 Products)

Synonyms: CENTD1 antibody, PARX antibody, Centd1 antibody, Gm148 antibody, mKIAA0580 antibody, ARAP2 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 antibody, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 antibody, ARAP2 antibody, Arap2 antibody, LOC100567363 antibody

Background: The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.,ARAP2,CENTD1,PARX,Signal Transduction,G protein signaling,Signal Transduction,ARAP2

Molecular Weight: 193 kDa

Gene ID: 116984

UniProt: Q8WZ64