ARTN antibody

Catalog No. ABIN6137156

Product Details anti-ARTN Antibody

Target: ARTN (Artemin (ARTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARTN antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of human ARTN

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARTN

Target: ARTN (Artemin (ARTN))

Alternative Name: ARTN (ARTN Products)

Synonyms: ARTN antibody, ENOVIN antibody, EVN antibody, NBN antibody, neublastin antibody, artemin antibody, ARTN antibody, Artn antibody

Background: This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.,ARTN,ART,ENOVIN,EVN,NBN,artemin,Cell Biology & Developmental Biology,Growth factor,Neuroscience,ARTN

Molecular Weight: 22 kDa/23 kDa/24 kDa

Gene ID: 9048

UniProt: Q5T4W7