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ATP6V1B1 antibody (AA 1-280)

ATP6V1B1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6137346
  • Target See all ATP6V1B1 Antibodies
    ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))
    Binding Specificity
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-280
    Reactivity
    • 58
    • 20
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 3
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 31
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6V1B1 antibody is un-conjugated
    Application
    • 49
    • 34
    • 32
    • 17
    • 6
    • 6
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    MAMEIDSRPG GLPGSSCNLG AAREHMQAVT RNYITHPRVT YRTVCSVNGP LVVLDRVKFA QYAEIVHFTL PDGTQRSGQV LEVAGTKAIV QVFEGTSGID ARKTTCEFTG DILRTPVSED MLGRVFNGSG KPIDKGPVVM AEDFLDINGQ PINPHSRIYP EEMIQTGISP IDVMNSIARG QKIPIFSAAG LPHNEIAAQI CRQAGLVKKS KAVLDYHDDN FAIVFAAMGV NMETARFFKS DFEQNGTMGN VCLFLNLAND PTIERIITPR LALTTAEFLA
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATP6V1B1 (NP_001683.2).
    Isotype
    IgG
    Top Product
    Discover our top product ATP6V1B1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))
    Alternative Name
    ATP6V1B1 (ATP6V1B1 Products)
    Synonyms
    ATP6B1 antibody, RTA1B antibody, VATB antibody, VMA2 antibody, VPP3 antibody, AW208839 antibody, Atp6b1 antibody, D630003L15 antibody, D630030L16Rik antibody, D630039P21Rik antibody, Vpp-3 antibody, Vpp3 antibody, ATPase H+ transporting V1 subunit B1 antibody, ATPase, H+ transporting, lysosomal V1 subunit B1 antibody, ATP6V1B1 antibody, Atp6v1b1 antibody
    Background
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.,ATP6V1B1,ATP6B1,RTA1B,VATB,VMA2,VPP3,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,ATP6V1B1
    Molecular Weight
    56 kDa
    Gene ID
    525
    UniProt
    P15313
    Pathways
    Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport
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