AUH antibody (AA 68-339)

Catalog No. ABIN6137369

Product Details anti-AUH Antibody

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Binding Specificity: AA 68-339

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AUH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSEMKTEDEL RVRHLEEENR GIVVLGINRA YGKNSLSKNL IKMLSKAVDA LKSDKKVRTI IIRSEVPGIF CAGADLKERA KMSSSEVGPF VSKIRAVIND IANLPVPTIA AIDGLALGGG LELALACDIR VAASSAKMGL VETKLAIIPG GGGTQRLPRA IGMSLAKELI FSARVLDGKE AKAVGLISHV LEQNQEGDAA YRKALDLARE FLPQGPVAMR VAKLAINQGM EVDLVTGLAI EEACYAQTIP TKDRLEGLLA FKEKRPPRYK GE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-339 of human AUH (NP_001689.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AUH

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Alternative Name: AUH (AUH Products)

Synonyms: C77140 antibody, W91705 antibody, wu:fb81b10 antibody, zgc:101057 antibody, AU RNA binding methylglutaconyl-CoA hydratase antibody, AU RNA binding protein/enoyl-coenzyme A hydratase antibody, AU RNA binding protein/enoyl-CoA hydratase antibody, AU RNA binding protein/enoyl-CoA hydratase S homeolog antibody, AUH antibody, Auh antibody, auh antibody, auh.S antibody

Background: This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.,AUH,AUH

Molecular Weight: 32 kDa/35 kDa

Gene ID: 549

UniProt: Q13825