BMF antibody (AA 1-184)

Catalog No. ABIN6137587

Product Details anti-BMF Antibody

Target: BMF (Bcl2 Modifying Factor (BMF))

Binding Specificity: AA 1-184

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMF antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MEPSQCVEEL EDDVFQPEDG EPVTQPGSLL SADLFAQSLL DCPLSRLQLF PLTHCCGPGL RPTSQEDKAT QTLSPASPSQ GVMLPCGVTE EPQRLFYGNA GYRLPLPASF PAVLPIGEQP PEGQWQHQAE VQIARKLQCI ADQFHRLHVQ QHQQNQNRVW WQILLFLHNL ALNGEENRNG AGPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human BMF (NP_277038.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Alternative Name: BMF (BMF Products)

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.,BMF,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cytoskeleton,Motor Proteins,BMF

Molecular Weight: 14 kDa/17 kDa/20 kDa

Gene ID: 90427

UniProt: Q96LC9