BAAT1 antibody (AA 652-821)

Catalog No. ABIN6137642

Product Details anti-BAAT1 Antibody

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Binding Specificity: AA 652-821

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AQGLELALVF LGQTLGPPRT HCPYAVALPE VAPAQPLTEA LRALCHVGLF DFAFCALFDC DRPVAQKSCD LLLFLRDKIA SYSSLREARG SPNTASAEAT LPRWRAGEQA QPPGDQEPEA VLAMLRSLDL EGLRSTLAES SDHVEKSPQS LLQDMLATGG FLQGDEADCY

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 652-821 of human BRAT1 (NP_689956.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAAT1

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Alternative Name: BRAT1 (C7orf27 Products)

Synonyms: C7orf27 antibody, BAAT1 antibody, RMFSL antibody, AA881470 antibody, Baat1 antibody, baat1 antibody, zgc:136845 antibody, BRCA1 associated ATM activator 1 antibody, BRCA1-associated ATM activator 1 antibody, BRAT1 antibody, Brat1 antibody, brat1 antibody

Background: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.,BRAT1,BAAT1,C7orf27,RMFSL,Epigenetics & Nuclear Signaling,DNA Damage & Repair,BRAT1

Molecular Weight: 30 kDa/31 kDa/88 kDa

Gene ID: 221927

UniProt: Q6PJG6