C1QA antibody (AA 23-245)

Catalog No. ABIN6137751

Product Details anti-C1QA Antibody

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Binding Specificity: AA 23-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDLCRAPDGK KGEAGRPGRR GRPGLKGEQG EPGAPGIRTG IQGLKGDQGE PGPSGNPGKV GYPGPSGPLG ARGIPGIKGT KGSPGNIKDQ PRPAFSAIRR NPPMGGNVVI FDTVITNQEE PYQNHSGRFV CTVPGYYYFT FQVLSQWEIC LSIVSSSRGQ VRRSLGFCDT TNKGLFQVVS GGMVLQLQQG DQVWVEKDPK KGHIYQGSEA DSVFSGFLIF PSA

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-245 of human C1QA (NP_057075.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-C1QA antibody (ABIN6137751)

Deng, Xu, Fang, Yu, Zhu, Chen, Liu, Zhou: "The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis." in: Frontiers in immunology, Vol. 9, pp. 1063, (2018) (PubMed).

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: C1QA (C1QA Products)

Background: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.,C1QA,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,C1QA

Molecular Weight: 26 kDa

Gene ID: 712

UniProt: P02745

Pathways: Complement System