C8B antibody (AA 55-350)

Catalog No. ABIN6137785

Product Details anti-C8B Antibody

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Binding Specificity: AA 55-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVDVTLMPID CELSSWSSWT TCDPCQKKRY RYAYLLQPSQ FHGEPCNFSD KEVEDCVTNR PCRSQVRCEG FVCAQTGRCV NRRLLCNGDN DCGDQSDEAN CRRIYKKCQH EMDQYWGIGS LASGINLFTN SFEGPVLDHR YYAGGCSPHY ILNTRFRKPY NVESYTPQTQ GKYEFILKEY ESYSDFERNV TEKMASKSGF SFGFKIPGIF ELGISSQSDR GKHYIRRTKR FSHTKSVFLH ARSDLEVAHY KLKPRSLMLH YEFLQRVKRL PLEYSYGEYR DLFRDFGTHY ITEAVL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 55-350 of human C8B (NP_000057.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C8B

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Alternative Name: C8B (C8B Products)

Synonyms: C82 antibody, 4930439B20Rik antibody, AI595927 antibody, complement C8 beta chain antibody, complement component 8, beta polypeptide antibody, C8B antibody, C8b antibody, c8b antibody

Background: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.,C8B,C82,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Blood,Serum Proteins,C8B

Molecular Weight: 67 kDa

Gene ID: 732

UniProt: P07358

Pathways: Complement System