CBLC antibody (AA 245-474)

Catalog No. ABIN6138006

Product Details anti-CBLC Antibody

Target: CBLC (Cbl proto-oncogene C (CBLC))

Binding Specificity: AA 245-474

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DEVQERLQAC RDKPGSYIFR PSCTRLGQWA IGYVSSDGSI LQTIPANKPL SQVLLEGQKD GFYLYPDGKT HNPDLTELGQ AEPQQRIHVS EEQLQLYWAM DSTFELCKIC AESNKDVKIE PCGHLLCSCC LAAWQHSDSQ TCPFCRCEIK GWEAVSIYQF HGQATAEDSG NSSDQEGREL ELGQVPLSAP PLPPRPDLPP RKPRNAQPKV RLLKGNSPPA ALGPQDPAPA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 245-474 of human CBLC (NP_036248.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CBLC

Target: CBLC (Cbl proto-oncogene C (CBLC))

Alternative Name: CBLC (CBLC Products)

Synonyms: CBL-3 antibody, CBL-SL antibody, RNF57 antibody, Cbl proto-oncogene C antibody, CBLC antibody, Cblc antibody

Background: This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CBLC,CBL-3,CBL-SL,RNF57,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,CBLC

Molecular Weight: 47 kDa/52 kDa

Gene ID: 23624

UniProt: Q9ULV8

Pathways: EGFR Signaling Pathway