CDKN2D antibody (AA 1-166)

Catalog No. ABIN6138350

Product Details anti-CDKN2D Antibody

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Binding Specificity: AA 1-166

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN2D antibody is un-conjugated

Application: Immunofluorescence (IF)

Sequence: MLLEEVRAGD RLSGAAARGD VQEVRRLLHR ELVHPDALNR FGKTALQVMM FGSTAIALEL LKQGASPNVQ DTSGTSPVHD AARTGFLDTL KVLVEHGADV NVPDGTGALP IHLAVQEGHT AVVSFLAAES DLHRRDARGL TPLELALQRG AQDLVDILQG HMVAPL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CDKN2D (NP_001791.1).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDKN2D

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Alternative Name: CDKN2D (CDKN2D Products)

Synonyms: ink4d antibody, p19 antibody, p19-ink4d antibody, CDKN2D antibody, ank2 antibody, INK4D antibody, p19-INK4D antibody, INK4d antibody, p19INK4d antibody, cyclin-dependent kinase inhibitor 2D S homeolog antibody, cyclin dependent kinase inhibitor 2D antibody, cyclin-dependent kinase inhibitor 2D antibody, Cyclin-dependent kinase 4 inhibitor D antibody, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) antibody, similar to cyclin-dependent kinase inhibitor 2D antibody, cdkn2d.S antibody, CDKN2D antibody, cdkn2d antibody, cdn2d antibody, Cdkn2d antibody

Background: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.,CDKN2D,INK4D,p19,p19-INK4D,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,CDKN2D

Molecular Weight: 17 kDa

Gene ID: 1032

UniProt: P55273

Pathways: Cell Division Cycle, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling