CHAF1B antibody (AA 270-559)

Catalog No. ABIN6138482

This Rabbit Polyclonal antibody specifically detects CHAF1B in WB and IHC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CHAF1B antibody (AA 270-559) (ABIN6138482)

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHAF1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHAF1B Antibody

Binding Specificity: AA 270-559

Sequence: SRKNLKRPIA HLPCPGKATL AVRCCPVYFE LRPVVETGVE LMSLPYRLVF AVASEDSVLL YDTQQSFPFG YVSNIHYHTL SDISWSSDGA FLAISSTDGY CSFVTFEKDE LGIPLKEKPV LNMRTPDTAK KTKSQTHRGS SPGPRPVEGT PASRTQDPSS PGTTPPQARQ APAPTVIRDP PSITPAVKSP LPGPSEEKTL QPSSQNTKAH PSRRVTLNTL QAWSKTTPRR INLTPLKTDT PPSSVPTSVI STPSTEEIQS ETPGDAQGSP PELKRPRLDE NKGGTESLDP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1 (NP_005432.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CHAF1B antibody (ABIN6138482)

Zaidan, Walker, Brown, Schaffer, Scalf, Shortreed, Iyer, Smith, Sridharan: "Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance." in: Stem cell reports, Vol. 10, Issue 2, pp. 627-641, (2019) (PubMed).

Target Details for CHAF1B

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Alternative Name: CHAF1B

Background: Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.,CHAF1B,CAF-1,CAF-IP60,CAF1,CAF1A,CAF1P60,MPHOSPH7,MPP7,Epigenetics & Nuclear Signaling,Chromatin Remodeling,CHAF1B

Molecular Weight: 61 kDa

Gene ID: 8208

UniProt: Q13112