CHRNA6 antibody (AA 350-440)

Catalog No. ABIN6138580

Product Details anti-CHRNA6 Antibody

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Binding Specificity: AA 350-440

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PQVLLMRWPL DKTRGTGSDA VPRGLARRPA KGKLASHGEP RHLKECFHCH KSNELATSKR RLSHQPLQWV VENSEHSPEV EDVINSVQFI A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-440 of human CHRNA6 (NP_004189.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNA6

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Alternative Name: CHRNA6 (CHRNA6 Products)

Synonyms: Acra6 antibody, Nica6 antibody, si:dkey-234d14.1 antibody, CHNRA6 antibody, cholinergic receptor nicotinic alpha 6 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 6 antibody, cholinergic receptor, nicotinic, alpha 6 antibody, Chrna6 antibody, CHRNA6 antibody, chrna6 antibody

Background: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.,CHRNA6,CHNRA6,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA6

Molecular Weight: 55 kDa/56 kDa

Gene ID: 8973

UniProt: Q15825