Claudin 4 antibody (C-Term)

Catalog No. ABIN6138690

Product Details anti-Claudin 4 Antibody

Target: Claudin 4 (CLDN4)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VGGKCTNCLE DESAKAKTMI VAGVVFLLAG LMVIVPVSWT AHNIIQDFYN PLVASGQKRE MGASLYVGWA ASGLLLLGGG LLCCNCPPRT DKPYSAKYSA ARSAAASNYV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN4 (NP_001296.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: CLDN4 (CLDN4 Products)

Synonyms: CPE-R antibody, CPER antibody, CPETR antibody, CPETR1 antibody, WBSCR8 antibody, hCPE-R antibody, Cep-r antibody, Cpetr antibody, Cpetr1 antibody, CLDN4 antibody, cper antibody, cpe-r antibody, cpetr antibody, cpetr1 antibody, hcpe-r antibody, wbscr8 antibody, claudin 4 antibody, claudin 4 L homeolog antibody, CLDN4 antibody, Cldn4 antibody, cldn4 antibody, cldn4.L antibody

Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.,CLDN4,CPE-R,CPER,CPETR,CPETR1,WBSCR8,hCPE-R,claudin-4,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN4

Molecular Weight: 22 kDa

Gene ID: 1364

UniProt: O14493

Pathways: Hepatitis C