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COL4A1 antibody (AA 1445-1669)

COL4A1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6138841
  • Target See all COL4A1 Antibodies
    COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
    Binding Specificity
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1445-1669
    Reactivity
    • 47
    • 23
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 4
    Rabbit
    Clonality
    • 44
    • 4
    Polyclonal
    Conjugate
    • 21
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL4A1 antibody is un-conjugated
    Application
    • 34
    • 23
    • 15
    • 9
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    GFLVTRHSQT IDDPQCPSGT KILYHGYSLL YVQGNERAHG QDLGTAGSCL RKFSTMPFLF CNINNVCNFA SRNDYSYWLS TPEPMPMSMA PITGENIRPF ISRCAVCEAP AMVMAVHSQT IQIPPCPSGW SSLWIGYSFV MHTSAGAEGS GQALASPGSC LEEFRSAPFI ECHGRGTCNY YANAYSFWLA TIERSEMFKK PTPSTLKAGE LRTHVSRCQV CMRRT
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1445-1669 of human COL4A1 (NP_001836.2).
    Isotype
    IgG
    Top Product
    Discover our top product COL4A1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
    Alternative Name
    COL4A1 (COL4A1 Products)
    Synonyms
    col4a1 antibody, wu:fc02g11 antibody, HANAC antibody, ICH antibody, POREN1 antibody, arresten antibody, Bru antibody, Col4a-1 antibody, Del(8)44H antibody, Raw antibody, Svc antibody, collagen, type IV, alpha 5 (Alport syndrome) antibody, collagen type IV alpha 1 chain antibody, collagen, type IV, alpha 1 antibody, col4a5 antibody, COL4A1 antibody, Col4a1 antibody
    Background
    This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.,COL4A1,BSVD,RATOR,Stem Cells,COL4A1
    Molecular Weight
    127 kDa/160 kDa
    Gene ID
    1282
    UniProt
    P02462
    Pathways
    Skeletal Muscle Fiber Development, Growth Factor Binding
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