COX7A2L antibody (AA 1-114)
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- Target See all COX7A2L Antibodies
- COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
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Binding Specificity
- AA 1-114
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COX7A2L antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MYYKFSGFTQ KLAGAWASEA YSPQGLKPVV STEAPPIIFA TPTKLTSDST VYDYAGKNKV PELQKFFQKA DGVPVYLKRG LPDQMLYRTT MALTVGGTIY CLIALYMASQ PKNK
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human COX7A2L (NP_004709.2).
- Isotype
- IgG
- Top Product
- Discover our top product COX7A2L Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
- Alternative Name
- COX7A2L (COX7A2L Products)
- Synonyms
- COX7AR antibody, COX7RP antibody, EB1 antibody, SIG81 antibody, SIG-81 antibody, Silg81 antibody, cytochrome c oxidase subunit 7A2 like antibody, cytochrome c oxidase subunit VIIa polypeptide 2-like antibody, COX7A2L antibody, Cox7a2l antibody
- Background
- Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.,COX7A2L,COX7AR,COX7RP,EB1,SIG81,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,COX7A2L
- Molecular Weight
- 12 kDa
- Gene ID
- 9167
- UniProt
- O14548
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