DAP3 antibody (AA 159-398)
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- Target See all DAP3 Antibodies
- DAP3 (Death-Associated Protein 3 (DAP3))
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Binding Specificity
- AA 159-398
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DAP3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- HLWVKNCRDL LQSSYNKQRF DQPLEASTWL KNFKTTNERF LNQIKVQEKY VWNKRESTEK GSPLGEVVEQ GITRVRNATD AVGIVLKELK RQSSLGMFHL LVAVDGINAL WGRTTLKRED KSPIAPEELA LVHNLRKMMK NDWHGGAIVS ALSQTGSLFK PRKAYLPQEL LGKEGFDALD PFIPILVSNY NPKEFESCIQ YYLENNWLQH EKAPTEEGKK ELLFLSNANP SLLERHCAYL
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 159-398 of human DAP3 (NP_387506.1).
- Isotype
- IgG
- Top Product
- Discover our top product DAP3 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DAP3 (Death-Associated Protein 3 (DAP3))
- Alternative Name
- DAP3 (DAP3 Products)
- Synonyms
- DAP-3 antibody, MRP-S29 antibody, MRPS29 antibody, bMRP-10 antibody, 4921514D13Rik antibody, im:6905684 antibody, death associated protein 3 antibody, DAP3 antibody, Dap3 antibody, dap3 antibody
- Background
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.,DAP3,DAP-3,MRP-S29,MRPS29,bMRP-10,S29mt,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,DAP3
- Molecular Weight
- 41 kDa/45 kDa
- Gene ID
- 7818
- UniProt
- P51398
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