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DDX3X antibody (AA 1-220)

DDX3X Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6139494
  • Target See all DDX3X Antibodies
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    Binding Specificity
    • 18
    • 15
    • 10
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-220
    Reactivity
    • 108
    • 42
    • 33
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 99
    • 9
    Rabbit
    Clonality
    • 99
    • 8
    Polyclonal
    Conjugate
    • 59
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DDX3X antibody is un-conjugated
    Application
    • 76
    • 43
    • 37
    • 26
    • 26
    • 17
    • 16
    • 13
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequence
    MSHVAVENAL GLDQQFAGLD LNSSDNQSGG STASKGRYIP PHLRNREATK GFYDKDSSGW SSSKDKDAYS SFGSRSDSRG KSSFFSDRGS GSRGRFDDRG RSDYDGIGSR GDRSGFGKFE RGGNSRWCDK SDEDDWSKPL PPSERLEQEL FSGGNTGINF EKYDDIPVEA TGNNCPPHIE SFSDVEMGEI IMGNIELTRY TRPTPVQKHA IPIIKEKRDL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DDX3X (NP_001347.3).
    Isotype
    IgG
    Top Product
    Discover our top product DDX3X Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    Alternative Name
    DDX3X (DDX3X Products)
    Synonyms
    DBX antibody, DDX14 antibody, DDX3 antibody, HLP2 antibody, D1Pas1-rs2 antibody, Ddx3 antibody, Fin14 antibody, An3 antibody, pl10 antibody, DDX3X antibody, DEAD-box helicase 3, X-linked antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked antibody, DEAD-box helicase 3, X-linked L homeolog antibody, DDX3X antibody, Ddx3x antibody, ddx3x.L antibody, ddx3x antibody
    Background
    The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.,DDX3X,CAP-Rf,DBX,DDX14,DDX3,HLP2,MRX102,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,DDX3X
    Molecular Weight
    71 kDa/73 kDa
    Gene ID
    1654
    UniProt
    O00571
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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