DUSP9 antibody

Catalog No. ABIN6139880

Product Details anti-DUSP9 Antibody

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human DUSP9

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:20 - 1:200,IF,1:20 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP9

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Alternative Name: DUSP9 (DUSP9 Products)

Synonyms: MKP-4 antibody, MKP4 antibody, Dusp4 antibody, Mpk4 antibody, Pyst3 antibody, DUSP9 antibody, dual specificity phosphatase 9 antibody, DUSP9 antibody, Dusp9 antibody

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.,DUSP9,MKP-4,MKP4,Signal Transduction,DUSP9

Molecular Weight: 41 kDa

Gene ID: 1852

UniProt: Q99956