DYNC2LI1 antibody (AA 1-352)
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- Target See all DYNC2LI1 Antibodies
- DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))
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Binding Specificity
- AA 1-352
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DYNC2LI1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MPSETLWEIA KAEVEKRGIN GSEGDGAEIA EKFVFFIGSK NGGKTTIILR CLDRDEPPKP TLALEYTYGR RAKGHNTPKD IAHFWELGGG TSLLDLISIP ITGDTLRTFS LVLVLDLSKP NDLWPTMENL LQATKSHVDK VIMKLGKTNA KAVSEMRQKI WNNMPKDHPQ DHELIDPFPV PLVIIGSKYD VFQDFESEKR KVICKTLRFV AHYYGASLMF TSKSEALLLK IRGVINQLAF GIDKSKSICV DQNKPLFITA GLDSFGQIGS PPVPENDIGK LHAHSPMELW KKVYEKLFPP KSINTLKDIK DPARDPQYAE NEVDEMRIQK DLELEQYKRS SSKSWKQIEL DS
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
- Isotype
- IgG
- Top Product
- Discover our top product DYNC2LI1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))
- Alternative Name
- DYNC2LI1 (DYNC2LI1 Products)
- Synonyms
- DYNC2LI1 antibody, 4933404O11Rik antibody, CGI-60 antibody, D2lic antibody, LIC3 antibody, mD2LIC antibody, D2LIC antibody, dynein cytoplasmic 2 light intermediate chain 1 antibody, DYNC2LI1 antibody, Dync2li1 antibody
- Background
- This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.,DYNC2LI1,CGI-60,D2LIC,LIC3,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Cytoskeleton,Motor Proteins,DYNC2LI1
- Molecular Weight
- 15 kDa/22 kDa/37 kDa/39 kDa
- Gene ID
- 51626
- UniProt
- Q8TCX1
- Pathways
- Hedgehog Signaling
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