EIF3L antibody (AA 1-230)
-
- Target See all EIF3L Antibodies
- EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))
-
Binding Specificity
- AA 1-230
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EIF3L antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- MSYPADDYES EAAYDPYAYP SDYDMHTGDP KQDLAYERQY EQQTYQVIPE VIKNFIQYFH KTVSDLIDQK VYELQASRVS SDVIDQKVYE IQDIYENSWT KLTERFFKNT PWPEAEAIAP QVGNDAVFLI LYKELYYRHI YAKVSGGPSL EQRFESYYNY CNLFNYILNA DGPAPLELPN QWLWDIIDEF IYQFQSFSQY RCKTAKKSEE EIDFLRSNPK IWNVHSVLNV
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human EIF3L (NP_057175.1).
- Isotype
- IgG
- Top Product
- Discover our top product EIF3L Primary Antibody
-
-
- Application Notes
- WB,1:1000 - 1:4000,IHC,1:50 - 1:200
- Comment
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))
- Alternative Name
- EIF3L (EIF3L Products)
- Synonyms
- wu:fb66c05 antibody, zgc:64147 antibody, EIF3EIP antibody, EIF3S11 antibody, EIF3S6IP antibody, HSPC021 antibody, HSPC025 antibody, MSTP005 antibody, 0610011H21Rik antibody, D15N1e antibody, Eif3eip antibody, Eif3ip antibody, Eif3s6ip antibody, HSP-66Y antibody, PAF67 antibody, eif3eip antibody, eif3s6ip antibody, eukaryotic translation initiation factor 3, subunit 6 interacting protein antibody, eukaryotic translation initiation factor 3 subunit L antibody, eukaryotic translation initiation factor 3, subunit L antibody, eukaryotic translation initiation factor 3 subunit L L homeolog antibody, eif3s6ip antibody, EIF3L antibody, Eif3l antibody, eif3l.L antibody
- Background
- Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3L,EIF3EIP,EIF3S11,EIF3S6IP,HSPC021,HSPC025,MSTP005,Epigenetics & Nuclear Signaling,EIF3L
- Molecular Weight
- 61 kDa/66 kDa
- Gene ID
- 51386
- UniProt
- Q9Y262
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-