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ERO1LB antibody (AA 34-230)

ERO1LB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6140294
  • Target See all ERO1LB Antibodies
    ERO1LB (ERO1-Like beta (ERO1LB))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 1
    AA 34-230
    Reactivity
    • 26
    • 22
    • 17
    Human
    Host
    • 37
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERO1LB antibody is un-conjugated
    Application
    • 33
    • 20
    • 17
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    QVTGVLDDCL CDIDSIDNFN TYKIFPKIKK LQERDYFRYY KVNLKRPCPF WAEDGHCSIK DCHVEPCPES KIPVGIKAGH SNKYLKMANN TKELEDCEQA NKLGAINSTL SNQSKEAFID WARYDDSRDH FCELDDERSP AAQYVDLLLN PERYTGYKGT SAWRVWNSIY EENCFKPRSV YRPLNPLAPS RGEDDGE
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 34-230 of human ERO1LB (NP_063944.3).
    Isotype
    IgG
    Top Product
    Discover our top product ERO1LB Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ERO1LB (ERO1-Like beta (ERO1LB))
    Alternative Name
    ERO1LB (ERO1LB Products)
    Synonyms
    RGD1563548 antibody, 1300013B24Rik antibody, 1700065B09Rik antibody, AI447560 antibody, ero1-beta antibody, endoplasmic reticulum oxidoreductase 1 beta antibody, ERO1-like beta (S. cerevisiae) antibody, Ero1b antibody, ERO1B antibody, Ero1lb antibody
    Background
    Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate, as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.,ERO1B,ERO1LB,Ero1beta,Signal Transduction,ERO1LB
    Molecular Weight
    16 kDa/53 kDa
    Gene ID
    56605
    UniProt
    Q86YB8
    Pathways
    SARS-CoV-2 Protein Interactome
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