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EZH1 antibody (AA 160-280)
EZH1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EZH1 Antibody
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Target
See all EZH1 Antibodies
EZH1
(Enhancer of Zeste Homolog 1 (EZH1))
Binding Specificity
All epitopes for EZH1 antibodies
AA 160-280
Reactivity
All reactivities for EZH1 antibodies
Human
Host
All hosts for EZH1 antibodies
Rabbit
Clonality
All clonalities for EZH1 antibodies
Polyclonal
Conjugate
All conjugates for EZH1 antibodies
This EZH1 antibody is un-conjugated
Application
All applications for EZH1 antibodies
Western Blotting (WB)
Sequence
GEEEMIPGSV LISDAVFLEL VDALNQYSDE EEEGHNDTSD GKQDDSKEDL PVTRKRKRHA IEGNKKSSKK QFPNDMIFSA IASMFPENGV PDDMKERYRE LTEMSDPNAL PPQCTPNIDG P
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human EZH1 (NP_001982.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-EZH1 antibody (ABIN6140390)
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Wang, Cao, Zhang, Yan, Xu, Wu, Wan, Zhang, Zhang, Qin, Xiao, Ye, Liu, Han, Wang, Mao, Wei, Chen : "A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. " in: The EMBO journal , Vol. 36 , Issue 9 , pp. 1243-1260 , (2017 ) (PubMed ).
Target Details for EZH1
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Target
EZH1
(Enhancer of Zeste Homolog 1 (EZH1))
Alternative Name
EZH1 (EZH1 Products )
Synonyms
KMT6B antibody, si:ch211-250i3.1 antibody, zgc:136829 antibody, AW557915 antibody, mKIAA0388 antibody, EZH1 antibody, enhancer of zeste 1 polycomb repressive complex 2 subunit antibody, EZH1 antibody, ezh1 antibody, Ezh1 antibody
Background
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009],EZH1,KMT6B,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Chromatin Remodeling,EZH1
Molecular Weight
68 kDa/76 kDa/80 kDa/85 kDa/86 kDa
Gene ID
2145
UniProt
Q92800
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