FADS2 antibody (AA 1-131)

Catalog No. ABIN6140434

Product Details anti-FADS2 Antibody

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Binding Specificity: AA 1-131

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FADS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGKGGNQGEG AAEREVSVPT FSWEEIQKHN LRTDRWLVID RKVYNITKWS IQHPGGQRVI GHYAGEDATD AFRAFHPDLE FVGKFLKPLL IGELAPEEPS QDHGKNSKIT EDFRALRKTA EDMNLFKTNH V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human FADS2 (NP_004256.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-FADS2 antibody (ABIN6140434)

Dong, Wang, Kao, Diaz, Tasset, Kaushik, Thiruthuvanathan, Zintiridou, Nieves, Dzieciatkowska, Reisz, Gavathiotis, DAlessandro, Will, Cuervo: "Chaperone-mediated autophagy sustains haematopoietic stem-cell function." in: Nature, Vol. 591, Issue 7848, pp. 117-123, (2021) (PubMed).

Target Details for FADS2

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Alternative Name: FADS2 (FADS2 Products)

Synonyms: D6D antibody, DES6 antibody, FADSD6 antibody, LLCDL2 antibody, SLL0262 antibody, TU13 antibody, FADS5 antibody, MSTP008 antibody, SCD1 antibody, SCDOS antibody, 2900042M13Rik antibody, Fadsd2 antibody, Fadsd6 antibody, DRD5/D6 antibody, wu:fb64c04 antibody, wu:fb69e08 antibody, zgc:112502 antibody, fatty acid desaturase 2 antibody, stearoyl-CoA desaturase antibody, fatty acid desaturase 2 L homeolog antibody, FADS2 antibody, SCD antibody, Fads2 antibody, fads2 antibody, fads2.L antibody

Background: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.,FADS2,D6D,DES6,FADSD6,LLCDL2,SLL0262,TU13,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Cardiovascular,Lipids,Fatty Acids,FADS2

Molecular Weight: 45 kDa/48 kDa/49 kDa/52 kDa

Gene ID: 9415

UniProt: O95864