Fibromodulin antibody (AA 19-376)

Catalog No. ABIN6140716

Product Details anti-Fibromodulin Antibody

Target: Fibromodulin (FMOD)

Binding Specificity: AA 19-376

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QYEDDPHWWF HYLRSQQSTY YDPYDPYPYE TYEPYPYGVD EGPAYTYGSP SPPDPRDCPQ ECDCPPNFPT AMYCDNRNLK YLPFVPSRMK YVYFQNNQIT SIQEGVFDNA TGLLWIALHG NQITSDKVGR KVFSKLRHLE RLYLDHNNLT RMPGPLPRSL RELHLDHNQI SRVPNNALEG LENLTALYLQ HNEIQEVGSS MRGLRSLILL DLSYNHLRKV PDGLPSALEQ LYMEHNNVYT VPDSYFRGAP KLLYVRLSHN SLTNNGLASN TFNSSSLLEL DLSYNQLQKI PPVNTNLENL YLQGNRINEF SISSFCTVVD VVNFSKLQVL RLDGNEIKRS AMPADAPLCL RLASLIEI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-376 of human FMOD (NP_002014.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD (FMOD Products)

Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.,FMOD,FM,SLRR2E,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Stem Cells,Mesenchymal Stem Cells,FMOD

Molecular Weight: 43 kDa

Gene ID: 2331

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process