FUS antibody (AA 297-526)

Catalog No. ABIN6140818

Product Details anti-FUS Antibody

Target: FUS (Fused in Sarcoma (FUS))

Binding Specificity: AA 297-526

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: TIESVADYFK QIGIIKTNKK TGQPMINLYT DRETGKLKGE ATVSFDDPPS AKAAIDWFDG KEFSGNPIKV SFATRRADFN RGGGNGRGGR GRGGPMGRGG YGGGGSGGGG RGGFPSGGGG GGGQQRAGDW KCPNPTCENM NFSWRNECNQ CKAPKPDGPG GGPGGSHMGG NYGDDRRGGR GGYDRGGYRG RGGDRGGFRG GRGGGDRGGF GPGKMDSRGE HRQDRRERPY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS (FUS Products)

Target Type: Viral Protein

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.,FUS,ALS6,ETM4,FUS1,HNRNPP2,POMP75,TLS,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,Signal Transduction,FUS

Molecular Weight: 53 kDa

Gene ID: 2521

UniProt: P35637