GEMIN8 antibody (AA 1-242)

Catalog No. ABIN6141056

Product Details anti-GEMIN8 Antibody

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Binding Specificity: AA 1-242

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAAVKASTSK ATRPWYSHPV YARYWQHYHQ AMAWMQSHHN AYRKAVESCF NLPWYLPSAL LPQSSYDNEA AYPQSFYDHH VAWQDYPCSS SHFRRSGQHP RYSSRIQAST KEDQALSKEE EMETESDAEV ECDLSNMEIT EELRQYFAET ERHREERRRQ QQLDAERLDS YVNADHDLYC NTRRSVEAPT ERPGERRQAE MKRLYGDSAA KIQAMEAAVQ LSFDKHCDRK QPKYWPVIPL KF

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human GEMIN8 (NP_060326.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GEMIN8

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Alternative Name: GEMIN8 (GEMIN8 Products)

Synonyms: FAM51A1 antibody, B130034M20Rik antibody, B930082C09Rik antibody, BC023488 antibody, gemin-8 antibody, gem nuclear organelle associated protein 8 antibody, gemin8 antibody, GEMIN8 antibody, Gemin8 antibody

Background: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.,GEMIN8,FAM51A1,Epigenetics & Nuclear Signaling,GEMIN8

Molecular Weight: 28 kDa

Gene ID: 54960

UniProt: Q9NWZ8

Pathways: Ribonucleoprotein Complex Subunit Organization