GSTa2 antibody (AA 1-222)
-
- Target See all GSTa2 Antibodies
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
-
Binding Specificity
- AA 1-222
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GSTa2 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- MAEKPKLHYS NIRGRMESIR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKEKA LIDMYIEGIA DLGEMILLLP FSQPEEQDAK LALIQEKTKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEESRKIF RF
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA2 (NP_000837.3).
- Isotype
- IgG
- Top Product
- Discover our top product GSTa2 Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000
- Comment
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
- Alternative Name
- GSTA2 (GSTa2 Products)
- Synonyms
- GSTA1 antibody, GST2 antibody, GSTA2-2 antibody, GTA2 antibody, GTH2 antibody, Gsta1 antibody, Gst2-2 antibody, Gstc-2 antibody, Gstc2 antibody, glutathione S-transferase alpha 2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 2 (Yc2) antibody, GSTA2 antibody, Gsta2 antibody
- Background
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.,GSTA2,GST2,GSTA2-2,GTA2,GTH2,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTA2
- Molecular Weight
- 25 kDa
- Gene ID
- 2939
- UniProt
- P09210
-