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HLA-DMA antibody (AA 27-233)

HLA-DMA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6141805
  • Target See all HLA-DMA Antibodies
    HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
    Binding Specificity
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 27-233
    Reactivity
    • 16
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 14
    • 2
    • 2
    Rabbit
    Clonality
    • 15
    • 3
    Polyclonal
    Conjugate
    • 13
    • 3
    • 1
    • 1
    This HLA-DMA antibody is un-conjugated
    Application
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VPEAPTPMWP DDLQNHTFLH TVYCQDGSPS VGLSEAYDED QLFFFDFSQN TRVPRLPEFA DWAQEQGDAP AILFDKEFCE WMIQQIGPKL DGKIPVSRGF PIAEVFTLKP LEFGKPNTLV CFVSNLFPPM LTVNWQHHSV PVEGFGPTFV SAVDGLSFQA FSYLNFTPEP SDIFSCIVTH EIDRYTAIAY WVPRNALPSD LLENVLC
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 27-233 of human HLA-DMA (NP_006111.2).
    Isotype
    IgG
    Top Product
    Discover our top product HLA-DMA Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
    Alternative Name
    HLA-DMA (HLA-DMA Products)
    Synonyms
    RT1.Ma antibody, RT1.DMa antibody, HLA-DMA antibody, H-2Ma antibody, H2-Ma antibody, D6S222E antibody, DMA antibody, HLADM antibody, RING6 antibody, RT1 class II, locus DMa antibody, SLA-DM alpha chain antibody, major histocompatibility complex, class II, DM alpha antibody, histocompatibility 2, class II, locus DMa antibody, RT1-DMa antibody, SLA-DMA antibody, DLA-DMA antibody, H2-DMa antibody, HLA-DMA antibody
    Background
    HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.,HLA-DMA,D6S222E,DMA,HLADM,RING6,major histocompatibility complex,class II,DM alpha,Immunology & Inflammation,Cardiovascular,Blood,HLA-DMA
    Molecular Weight
    29 kDa
    Gene ID
    3108
    UniProt
    P28067
    Pathways
    Cancer Immune Checkpoints
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