HSD17B4 antibody (AA 437-736)

Catalog No. ABIN6142010

Product Details anti-HSD17B4 Antibody

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Binding Specificity: AA 437-736

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SGVVIIMDVY SYSEKELICH NQFSLFLVGS GGFGGKRTSD KVKVAVAIPN RPPDAVLTDT TSLNQAALYR LSGDWNPLHI DPNFASLAGF DKPILHGLCT FGFSARRVLQ QFADNDVSRF KAIKARFAKP VYPGQTLQTE MWKEGNRIHF QTKVQETGDI VISNAYVDLA PTSGTSAKTP SEGGKLQSTF VFEEIGRRLK DIGPEVVKKV NAVFEWHITK GGNIGAKWTI DLKSGSGKVY QGPAKGAADT TIILSDEDFM EVVLGKLDPQ KAFFSGRLKA RGNIMLSQKL QMILKDYAKL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human HSD17B4 (NP_000405.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Alternative Name: HSD17B4 (HSD17B4 Products)

Synonyms: zgc:55545 antibody, zgc:77300 antibody, CG3415 antibody, DmMFE-2 antibody, Dmel\\CG3415 antibody, MFE-2 antibody, DBP antibody, MPF-2 antibody, PRLTS1 antibody, SDR8C1 antibody, 17-beta-HSD antibody, 17[b]-HSD antibody, 4 antibody, MFP2 antibody, Mfp-2 antibody, perMFE-2 antibody, hydroxysteroid (17-beta) dehydrogenase 4 antibody, hydroxysteroid 17-beta dehydrogenase 4 antibody, peroxisomal Multifunctional enzyme type 2 antibody, hsd17b4 antibody, HSD17B4 antibody, Mfe2 antibody, Hsd17b4 antibody

Background: The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,HSD17B4,DBP,MFE-2,MPF-2,PRLTS1,SDR8C1,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,HSD17B4

Molecular Weight: 77 kDa/79 kDa/83 kDa

Gene ID: 3295

UniProt: P51659

Pathways: Monocarboxylic Acid Catabolic Process