The Biotin-conjugated Mouse Monoclonal anti-CRP antibody (Clone C7) (ABIN614250) specifically detects CRP in EIA and ELISA (Detection).
The antibody is reactive with Human samples.
This antibody recognizes Human CRP, an 117 kDa acute phase protein, it recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
CRP
Reactivity: Rat
WB, IHC, ICC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target
CRP
(C-Reactive Protein (CRP))
Background
The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa, physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.Synonyms: C Reactive Protein, PTX1, Pentraxin-related