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MAN2B1 antibody (AA 640-850)

MAN2B1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6143456
  • Target See all MAN2B1 Antibodies
    MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))
    Binding Specificity
    • 4
    • 1
    AA 640-850
    Reactivity
    • 6
    • 1
    Human
    Host
    • 4
    • 3
    Rabbit
    Clonality
    • 6
    • 1
    Polyclonal
    Conjugate
    • 7
    This MAN2B1 antibody is un-conjugated
    Application
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TFFWYNASIG DNESDQASGA YIFRPNQQKP LPVSRWAQIH LVKTPLVQEV HQNFSAWCSQ VVRLYPGQRH LELEWSVGPI PVGDTWGKEV ISRFDTPLET KGRFYTDSNG REILERRRDY RPTWKLNQTE PVAGNYYPVN TRIYITDGNM QLTVLTDRSQ GGSSLRDGSL ELMVHRRLLK DDGRGVSEPL MENGSGAWVR GRHLVLLDTA Q
    Cross-Reactivity
    Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 640-850 of human MAN2B1 (NP_000519.2).
    Isotype
    IgG
    Top Product
    Discover our top product MAN2B1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))
    Alternative Name
    MAN2B1 (MAN2B1 Products)
    Synonyms
    AW107687 antibody, LAMAN antibody, Laman antibody, Manb antibody, MANB antibody, mannosidase alpha class 2B member 1 antibody, mannosidase, alpha, class 2B, member 1 antibody, mannosidase 2, alpha B1 antibody, MAN2B1 antibody, man2b1 antibody, Man2b1 antibody
    Background
    This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MAN2B1,LAMAN,MANB,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,MAN2B1
    Molecular Weight
    113 kDa
    Gene ID
    4125
    UniProt
    O00754
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