MBNL2 antibody (AA 160-260)
Quick Overview for MBNL2 antibody (AA 160-260) (ABIN6143603)
Target
See all MBNL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 160-260
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Sequence
- PPVTVPGSTA TQKLLRTDKL EVCREFQRGN CARGETDCRF AHPADSTMID TSDNTVTVCM DYIKGRCMRE KCKYFHPPAH LQAKIKAAQH QANQAAVAAQ A
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human MBNL2 (NP_659002.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MBNL2 (Muscleblind-Like 2 (MBNL2))
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Alternative Name
- MBNL2
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Background
- This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.,MBNL2,MBLL,MBLL39,PRO2032,Epigenetics & Nuclear Signaling,RNA Binding,MBNL2
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Molecular Weight
- 39 kDa/40 kDa
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Gene ID
- 10150
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UniProt
- Q5VZF2
Target
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