MRPL45 antibody (AA 57-306)

Catalog No. ABIN6144020

Product Details anti-MRPL45 Antibody

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Binding Specificity: AA 57-306

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL45 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MQHARKAGLV IPPEKSDRSI HLACTAGIFD AYVPPEGDAR ISSLSKEGLI ERTERMKKTM ASQVSIRRIK DYDANFKIKD FPEKAKDIFI EAHLCLNNSD HDRLHTLVTE HCFPDMTWDI KYKTVRWSFV ESLEPSHVVQ VRCSSMMNQG NVYGQITVRM HTRQTLAIYD RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI LKTVMIPGPQ LKPEEEYEEA QGEAQKPQLA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 57-306 of human MRPL45 (NP_115727.5).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL45

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Alternative Name: MRPL45 (MRPL45 Products)

Synonyms: L45mt antibody, MRP-L45 antibody, 2600005P05Rik antibody, AU043542 antibody, R75241 antibody, mrlp45 antibody, mitochondrial ribosomal protein L45 antibody, mitochondrial ribosomal protein L45 L homeolog antibody, Mrpl45 antibody, MRPL45 antibody, mrpl45.L antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.,MRPL45,L45mt,MRP-L45,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,Nucleotide metabolism,MRPL45

Molecular Weight: 35 kDa

Gene ID: 84311

UniProt: Q9BRJ2