MTMR3 antibody (AA 640-810)

Catalog No. ABIN6144158

Product Details anti-MTMR3 Antibody

Target: MTMR3 (Myotubularin Related Protein 3 (MTMR3))

Binding Specificity: AA 640-810

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: KWQEHRRSLE LSSLAGPGED PLSADSLGKP TRVPGGAELS VAAGVAEGQM ENILQEATKE ESGVEEPAHR AGIEIQEGKE DPLLEKESRR KTPEASAIGL HQDPELGDAA LRSHLDMSWP LFSQGISEQQ SGLSVLLSSL QVPPRGEDSL EVPVEQFRIE EIAEGREEAV L

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 640-810 of human MTMR3 (NP_066576.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTMR3

Target: MTMR3 (Myotubularin Related Protein 3 (MTMR3))

Alternative Name: MTMR3 (MTMR3 Products)

Background: This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.,MTMR3,FYVE-DSP1,ZFYVE10,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Regulators,MTMR3

Molecular Weight: 129 kDa/130 kDa/133 kDa

Gene ID: 8897

UniProt: Q13615

Pathways: Inositol Metabolic Process