NDUFV1 antibody (AA 1-250)

Catalog No. ABIN6144498

Product Details anti-NDUFV1 Antibody

Target: NDUFV1 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1))

Binding Specificity: AA 1-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFV1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MLATRRLLGW SLPARVSVRF SGDTTAPKKT SFGSLKDEDR IFTNLYGRHD WRLKGSLSRG DWYKTKEILL KGPDWILGEI KTSGLRGRGG AGFPTGLKWS FMNKPSDGRP KYLVVNADEG EPGTCKDREI LRHDPHKLLE GCLVGGRAMG ARAAYIYIRG EFYNEASNLQ VAIREAYEAG LIGKNACGSG YDFDVFVVRG AGAYICGEET ALIESIEGKQ GKPRLKPPFP ADVGVFGCPT TVANVETVAV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NDUFV1 (NP_009034.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDUFV1

Target: NDUFV1 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1))

Alternative Name: NDUFV1 (NDUFV1 Products)

Synonyms: GB17095 antibody, uqor1 antibody, DDBDRAFT_0188174 antibody, DDBDRAFT_0191420 antibody, DDB_0188174 antibody, DDB_0191420 antibody, wu:fc01f01 antibody, wu:fc12f12 antibody, zgc:86620 antibody, CI-51kD antibody, CI-51K antibody, CI51KD antibody, UQOR1 antibody, NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial antibody, NADH:ubiquinone oxidoreductase core subunit V1 antibody, NADH dehydrogenase ubiquinone flavoprotein 1 antibody, NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa antibody, NADH dehydrogenase (ubiquinone) flavoprotein 1 antibody, NADH:ubiquinone oxidoreductase core subunit V1 L homeolog antibody, LOC408367 antibody, NDUFV1 antibody, ndufv1 antibody, Ndufv1 antibody, LOC100179486 antibody, ndufv1.L antibody

Background: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I, a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction, a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,NDUFV1,CI-51K,CI51KD,UQOR1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,NDUFV1

Molecular Weight: 49 kDa/50 kDa

Gene ID: 4723

UniProt: P49821