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NUDT15 antibody (AA 1-164)
NUDT15
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUDT15 Antibody
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Target
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NUDT15
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
Binding Specificity
All epitopes for NUDT15 antibodies
AA 1-164
Reactivity
All reactivities for NUDT15 antibodies
Human
Host
All hosts for NUDT15 antibodies
Rabbit
Clonality
All clonalities for NUDT15 antibodies
Polyclonal
Conjugate
All conjugates for NUDT15 antibodies
This NUDT15 antibody is un-conjugated
Application
All applications for NUDT15 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
MTASAQPRGR RPGVGVGVVV TSCKHPRCVL LGKRKGSVGA GSFQLPGGHL EFGETWEECA QRETWEEAAL HLKNVHFASV VNSFIEKENY HYVTILMKGE VDVTHDSEPK NVEPEKNESW EWVPWEELPP LDQLFWGLRC LKEQGYDPFK EDLNHLVGYK GNHL
Cross-Reactivity
Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:100 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NUDT15
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Target
NUDT15
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
Alternative Name
NUDT15 (NUDT15 Products )
Synonyms
MTH2 antibody, RP11-90M2.1 antibody, 6530403O17 antibody, A730068G11Rik antibody, nudix hydrolase 15 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antibody, NUDT15 antibody, Nudt15 antibody
Background
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.,NUDT15,MTH2,NUDT15D,Epigenetics & Nuclear Signaling,NUDT15
Molecular Weight
18 kDa
Gene ID
55270
UniProt
Q9NV35
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